This is not a regression. Tested in //UE5/Release-5.0 CL20979098
The transform of a Virtual Bone can be changed in the Skeleton but isn't preserved this has caused some confusion with users.
Expect Results:
Either:
Actual Results:
The Virtual Bone is reset to the parent's position.
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-174819 in the post.