Editor shortcuts will not work if you launch the editor with a non-Latin-based language (ex. Russian, Chinese). The editor must be closed and restarted with English (or possibly any Latin alphabet-based language) for shortcuts to work again.
Tested in:
4.23.1 CL#9631420
4.24 CL#9962040
4.25 CL#Main
Results: Shortcut keys no longer work in the editor
Expected: Shortcut keys to still work even when launching the editor with a different language.
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There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-83036 in the post.